Combination

Mixing DXM and MAOIs

DissociativeAntidepressant
DXM also called
robo, robitussin, robotussin, syrup, dex, cough syrup
MAOIs also called
maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
Verdict

Dangerous

High risk of serotonin syndrome

Risk / Physical + headspace

This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.

Can you mix DXM and MAOIs?

High risk of death or life-changing injury. Do not combine.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Related combinations

DXM withWhat not to mix with DXM →
MAOIs withWhat not to mix with MAOIs →
All combinations →

Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.