Combination
Mixing Amphetamines and MAOIs
StimulantAntidepressant
- Amphetamines also called
- adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
- MAOIs also called
- maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
Verdict
Dangerous
MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably. MAO-A inhibitors with amphetamine can lead to hypertensive crises.
Risk / Physical
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Can you mix Amphetamines and MAOIs?
High risk of death or life-changing injury. Do not combine.
- Amphetamines
- Prescription and street speed — Adderall, dexamphetamine
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.