Combination

Mixing GHB / GBL and Methamphetamine

DepressantStimulant
GHB / GBL also called
ghb, gbl, liquid ecstasy
Methamphetamine also called
meth, crystal, crystal meth, ice, tina, shard
Verdict

Caution

Stimulants increase respiration rate allowing for a higher dose of sedatives than normal. If the stimulant wears off first the opiate may overcome the individual and cause respiratory arrest.

Risk / Physical

The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.

Can you mix GHB / GBL and Methamphetamine?

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

This is a class-level answer, inherited from Amphetamines. Nothing specific to this exact pair is documented, so treat it as the default for the class rather than a measurement of these two drugs together.

Methamphetamine
Roughly twice as potent, and lasts three to four times as long
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Related combinations

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Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.