Combination

Mixing Lithium and Mushrooms

OtherPsychedelic
Lithium also called
lithium carbonate, lithobid, mood stabilizer
Mushrooms also called
shrooms, psilocybin, psilocybin mushrooms, mushroom, psylocybin, caps
Verdict

Dangerous

There are a large number of reports indicating a high seizure and psychosis risk from this combination.

Risk / Physical + headspace

This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.

Can you mix Lithium and Mushrooms?

High risk of death or life-changing injury. Do not combine.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.