Combination

Mixing LSD and Mephedrone

PsychedelicStimulant
LSD also called
acid, lsd-25, cid, lucy, tabs, blotter
Mephedrone also called
4-mmc, 4mmc, meow, m-cat, 4-methylmethcathinone, bath salts
Verdict

Caution

The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops, in addition to the possible negative side effects of coming down from said stimulant while on a psychedelic. In extreme cases, stimulants, especially in combination can result in severe vasoconstriction, tachycardia, hypertension, and heart failure.

Risk / Headspace

The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.

Can you mix LSD and Mephedrone?

Carries risk that is worth understanding before combining. Reduce doses and do not use alone.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.