Combination

Mixing Mescaline and Mushrooms

PsychedelicPsychedelic
Mescaline also called
peyote, san pedro, san-pedro, mesc, buttons
Mushrooms also called
shrooms, psilocybin, psilocybin mushrooms, mushroom, psylocybin, caps
Verdict

Low risk, increased effect

Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.

Can you mix Mescaline and Mushrooms?

Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.