Mixing Methamphetamine and SSRIs
- Methamphetamine also called
- meth, crystal, crystal meth, ice, tina, shard
- SSRIs also called
- ssri, zoloft, sertraline, lexapro, escitalopram, prozac
Caution
SSRIs blunt methamphetamine's effect, which invites redosing, while adding serotonin toxicity risk. Some SSRIs also inhibit CYP2D6 and slow its clearance, so the dose you take lasts even longer than usual.
The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.
Can you mix Methamphetamine and SSRIs?
Carries risk that is worth understanding before combining. Reduce doses and do not use alone.
- Methamphetamine
- Roughly twice as potent, and lasts three to four times as long
- The Main Molecular Mechanisms Underlying Methamphetamine-Induced Neurotoxicity and Implications for Pharmacological Treatment. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5994595/
- Neurobiology and Clinical Manifestations of Methamphetamine Neurotoxicity. Psychiatric Times. https://www.psychiatrictimes.com/view/neurobiology-and-clinical-manifestations-methamphetamine-neurotoxicity
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.