Combination
Mixing 2C-x and MAOIs
PsychedelicAntidepressant
- 2C-x also called
- 2c-b, 2c-i, 2c-e, 2c-d, 2cb, 2ci
- MAOIs also called
- maoi, nardil, phenelzine, parnate, tranylcypromine, marplan
Verdict
Caution
MAO-B inhibitors can increase the potency and duration of phenethylamines unpredictably
Risk / Headspace
The risk here is to the experience — intensity, panic, thought loops, confusion. Physical harm is unlikely at ordinary doses. Setting, company and dose do most of the work.
Can you mix 2C-x and MAOIs?
Carries risk that is worth understanding before combining. Reduce doses and do not use alone.
TripSit drug combination chart, retrieved 2026-08-20. View the dataset.
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
All combinations →Rated caution. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.