Combination

Mixing Cannabis and MDMA

DepressantEmpathogen
Cannabis also called
weed, pot, marijuana, thc, hash, edibles
MDMA also called
molly, ecstasy, ecstacy, xtc, mandy, pills
Verdict

Low risk, increased effect

Large amounts of cannabis may cause strong and somewhat unpredictable experiences in combination with MDMA. Cannabis should be saved for towards the end of the experience if possible.

Can you mix Cannabis and MDMA?

Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

Open this in the checker

Related combinations

Cannabis withWhat not to mix with Cannabis →
MDMA withWhat not to mix with MDMA →
All combinations →

Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.