Combination

Mixing Cannabis and Pregabalin

DepressantDepressant
Cannabis also called
weed, pot, marijuana, thc, hash, edibles
Pregabalin also called
lyrica, pregablin, gabapentin, gaba
Verdict

Low risk, increased effect

Both substances may increase each other's side effects, such as sedation, lowered blood pressure, and raised heart rate.

Can you mix Cannabis and Pregabalin?

Low risk of harm, but the effects amplify each other. Doses that are fine alone can be far too much together.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

Open this in the checker

Related combinations

Cannabis withWhat not to mix with Cannabis →
Pregabalin withWhat not to mix with Pregabalin →
All combinations →

Rated low / synergy. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.