Combination

Mixing DXM and Lithium

DissociativeOther
DXM also called
robo, robitussin, robotussin, syrup, dex, cough syrup
Lithium also called
lithium carbonate, lithobid, mood stabilizer
Verdict

Dangerous

There is a risk of serotonin syndrome when combining Lithium with DXM.

Risk / Physical + headspace

This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.

Can you mix DXM and Lithium?

High risk of death or life-changing injury. Do not combine.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.

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Related combinations

DXM withWhat not to mix with DXM →
Lithium withWhat not to mix with Lithium →
All combinations →

Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.