Combination
Mixing Diphenhydramine and PCP
DeliriantDissociative
- Diphenhydramine also called
- benadryl, dph, sleep aid, zzzquil, unisom
- PCP also called
- phencyclidine, angel dust, angeldust, wet, sherm
Verdict
Dangerous
Consistent with diphenhydramine's rating against other dissociatives: strongly additive delirium, confusion and amnesia, with a high chance of behaviour that neither substance alone would produce and no reliable memory of it.
Risk / Physical + headspace
This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.
Can you mix Diphenhydramine and PCP?
High risk of death or life-changing injury. Do not combine.
- Serotonin Syndrome: Mechanisms, Diagnosis, High-Risk Interactions. https://psychopharmacologyinstitute.com/publication/serotonin-syndrome-mechanisms-diagnosis-high-risk-interactions-and-management/
- Diphenhydramine interaction profile. Drugs.com. https://www.drugs.com/drug-interactions/melatonin.html
Checking more than two?
Combinations of three or more carry risks that no pair-by-pair chart can show. The checker rates every pair at once and flags the whole-mix ones on top.
Open this in the checkerRelated combinations
Diphenhydramine withWhat not to mix with Diphenhydramine →
Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.