Combination

Mixing 5-MeO-xxT and Amphetamines

PsychedelicStimulant
5-MeO-xxT also called
5-meo-dmt, 5-meo-mipt, 5-meo-dipt, foxy, toad
Amphetamines also called
adderall, speed, amphetamine, dexedrine, vyvanse, lisdexamfetamine
Verdict

Unsafe

The anxiogenic and focusing effects of stimulants increase the chance of unpleasant thought loops. The combination is generally unnecessary because of the stimulating effects of psychedelics.

Risk / Physical + headspace

This combination carries bodily risk and can go badly psychologically. The headspace part often arrives first and makes the physical part harder to notice.

Can you mix 5-MeO-xxT and Amphetamines?

Risk of serious physical or psychological harm. Not recommended under any circumstances.

Amphetamines
Prescription and street speed — Adderall, dexamphetamine
Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

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Rated unsafe. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.