Combination

Mixing Cocaine and Lithium

StimulantOther
Cocaine also called
coke, crack, blow, snow, yayo
Lithium also called
lithium carbonate, lithobid, mood stabilizer
Verdict

Low risk, decreased effect

Lithium may inhibit some of the recreational effects of cocaine.

Can you mix Cocaine and Lithium?

Low risk of harm from the combination, but one substance is expected to blunt the other. Redosing to chase the missing effect is the usual way this turns dangerous.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Rated low / decrease. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.