Combination

Mixing Alcohol and Benzodiazepines

DepressantDepressant
Alcohol also called
booze, beer, wine, liquor, ethanol, etoh
Benzodiazepines also called
benzodiazepine, benzos, benzo, xanax, alprazolam, valium
Verdict

Dangerous

Ethanol ingestion may potentiate the CNS effects of many benzodiazepines. The two substances potentiate each other strongly and unpredictably, very rapidly leading to unconsciousness. While unconscious, vomit aspiration is a risk if not placed in the recovery position. Blacking out and memory loss is almost certain.

Risk / Physical

The risk here is to the body — breathing, heart, temperature or organs. Set limits before you start, because this kind of harm does not announce itself in time to react.

Can you mix Alcohol and Benzodiazepines?

High risk of death or life-changing injury. Do not combine.

Source

TripSit drug combination chart, retrieved 2026-08-20. View the dataset.

Checking more than two?

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Rated dangerous. Educational information only, not medical advice. Absence of a documented interaction is not evidence of safety.